Find closest multiple of $50$ to $421$. We see that $8 \times 50 = 400$ is the nearest. Now subtract $400$ from $421$ to get reminder $21$. Add $8$ to quotient.
Since $21$ is less than $50$, stop the division. The reminder is $21$. The topmost line $008$ is the quotient. Remove all zeros at the start of the quotient to get the actual quotient $8$.