$${ 1 }^{ 2 } { 6 }^{ 2 } { 9 }^{ 2 } \frac{ { 4 }^{ 2 } }{ }$$
$46656$
$$1\times 6^{2}\times 9^{2}\times \frac{4^{2}}{1}$$
$$1\times 36\times 9^{2}\times \frac{4^{2}}{1}$$
$$36\times 9^{2}\times \frac{4^{2}}{1}$$
$$36\times 81\times \frac{4^{2}}{1}$$
$$2916\times \frac{4^{2}}{1}$$
$$2916\times \frac{16}{1}$$
$$2916\times 16$$
$$46656$$
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$2^{6}\times 3^{6}$