Variable $x$ cannot be equal to $0$ since division by zero is not defined. Multiply both sides of the equation by $200x$, the least common multiple of $x,50,8$.
$$200\times 200=4x\times 80\times \frac{4}{8}$$
Multiply $200$ and $200$ to get $40000$.
$$40000=4x\times 80\times \frac{4}{8}$$
Multiply $4$ and $80$ to get $320$.
$$40000=320x\times \frac{4}{8}$$
Reduce the fraction $\frac{4}{8}$ to lowest terms by extracting and canceling out $4$.
$$40000=320x\times \frac{1}{2}$$
Multiply $320$ and $\frac{1}{2}$ to get $\frac{320}{2}$.
$$40000=\frac{320}{2}x$$
Divide $320$ by $2$ to get $160$.
$$40000=160x$$
Swap sides so that all variable terms are on the left hand side.